identify two control mechanism glycolysis, from the given option 1. cyclic AMP dependent phosphorylation inactivates glycogen synthase 2. active FBPase2 decrease [fructose 2, 6 bisphosphate] 3. inactive GLUT4 receptor inhibit glucose uptake 4. no change occur in the abscence of insulin 5. lack of insulin activates acetyl CoA carboxylase
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For each pathway, identify the control mechanism or mechanisms responsible for the change you predict. fatty acid synthesis Lack of insulin inactivates acetyl-CoA carboxylase. Answer Bank Lack of insulin inactivates acetyl-CoA carboxylase glycolysis No change occurs in the absence of insulin. Active FBPase-2 decreases [fructose 2,6-bisphosphate]. glycogen synthesis Cyclic AMP-dependent phosphorylation inactivates glycogen synthase. Inactive GLUT4 receptors inhibit glucose uptake. gluconeogenesis Inactive GLUT4 receptors inhibit glucose uptake. No change occurs in the absence of insulin. Cyclic AMP-dependent phosphorylation inactivates glycogen synthase pentose phosphate pathway Active FBPase-2 decreases [fructose 2,6-bisphosphate].
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Both glycogenesis and glycogenolysis are controlled primarily by the interplay between the two hormones insulin and ________. 1) Glycogen synthetase 2) Glucagon 3) Fructose kinase 4) Glucose hydrolyase 5) Pentose kinase
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Which are true regarding Insulin: 1) Insulin leads to activation of phosphatase PP1, which dephosphorylated Glycogen Synthase (GS) leading to a decrease in glycogen synthesis. 2) Insulin leads to the phosphorylation of Acetyl-CoA carboxylase, which leads to increased FA synthesis. 3) Insulin leads to the dephosphorylation of Acetyl-CoA carboxylase (ACC), which leads to increased FA synthesis. 4) Insulin activated protein phosphatase (PP1) PP1 dephosphorylates kinase, leading to less phosphorylation in glycogen phosphorylase. A reduction in phosphorylated Glycogen phosphorylase leads to a reduction in glycogenolysis. 5) Insulin secreted by beta cells in pancreas in response to low glucose levels.
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