If hemoglobin has such a high affinity for oxygen, how is it able to release oxygen for use by tissue? How does exercise specifically affect the release of oxygen from hemoglobin? How is this process reversed at the lungs?
Added by Diane D.
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This binding is facilitated by the iron atoms in the heme groups of hemoglobin. When hemoglobin reaches the tissues, the oxygen concentration is lower, and this causes a conformational change in the hemoglobin molecule, which weakens the bond between hemoglobin Show more…
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