If this is part of the wildtype mRNA to be translated, which of the following DNA sequences would represent a mutation in the coding strand of the DNA that changes one amino acid of the protein? 5'-AUG-UCU-UCG-UUA-UCC-UUG-3' First position (5' end) U C A G U UUU Phe UCU Ser UAU Tyr UGU Cys U UUC UCC UAC UGC C UUA Leu UCA UAA Stop UGA Stop A UUG UCG UAG Stop UGG Trp G C CUU Leu CCU Pro CAU His CGU Arg U CUC CCC CAC CGC C CUA CCA CAA Gln CGA A CUG CCG CAG CGG G A AUU Ile ACU Thr AAU Asn AGU Ser U AUC ACC AAC AGC C AUA ACA AAA Lys AGA Arg A AUG Met ACG AAG AGG G G GUU Val GCU Ala GAU Asp GGU Gly U GUC GCC GAC GGC C GUA GCA GAA Glu GGA A GUG GCG GAG GGG G Third position (3' end) Amino acid names Ala = alanine Gln = glutamine Leu = leucine Ser = serine Arg = arginine Glu = glutamate Lys = lysine Thr = threonine Asn = asparagine Gly = glycine Met = methionine Trp = tryptophan Asp = aspartate His = histidine Phe = phenylalanine Tyr = Tyrosine Cys = cysteine Ile = isoleucine Pro = proline Val = valine 5'-ATG-TCT-TCG-TGA-TCC-TTG-3' 5'-ATG-TCT-TCG-TTA-TCC-TTG-3' 5'-ATG-TCC-TCG-TTA-TCC-TTG-3' 5'-ATG-TCT-TCG-TTA-TCC-TTT-3'
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First, we need to find the corresponding coding DNA sequence for the given mRNA sequence. The mRNA sequence is 5'-AUG-UCU-UCG-UUA-UCC-UUG-3'. Using the base pairing rules (A pairs with U, and C pairs with G), we can find the coding DNA sequence as Show more…
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