Imagine that you sampled a population of dung beetles, and discovered that allele frequencies were A1 = 0.24 and A2 = 0.76. You genotyped individuals in your sample, and calculated the following genotype frequencies: A1A1 homozygotes = 0.01, A1A2 heterozygotes = 0.44, and A2A2 homozygotes = 0.53. Is your population in Hardy-Weinberg equilibrium? What evidence leads you to arrive at your answer? This population is not in Hardy-Weinberg equilibrium because there is an excess of heterozygotes and a deficiency of homozygotes, compared to Hardy-Weinberg expectations. This population is not in Hardy-Weinberg equilibrium because allele frequencies have changed. This population is not in Hardy-Weinberg equilibrium because there is an excess of homozygotes and a deficiency of heterozygotes, compared to Hardy-Weinberg expectations. This population is in Hardy-Weinberg equilibrium because the observed genotype frequencies perfectly match Hardy-Weinberg expectations.
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24 and A2 = 0.76. Expected frequency of A1A1 homozygotes: $(0.24)^2 = 0.0576$ Expected frequency of A1A2 heterozygotes: $2(0.24)(0.76) = 0.3648$ Expected frequency of A2A2 homozygotes: $(0.76)^2 = 0.5776$ Now, let's compare these expected frequencies with the Show more…
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You perform a χ² test of the hypothesis that the population shows the genotype frequencies expected under Hardy-Weinberg equilibrium at one of the loci summarized in the figure in the previous question. You get a value of the statistic of χ² = 7.56. The critical value of the statistic at the 5% significance level is χ² = 3.84. What do you conclude? The allele frequencies deviate significantly from the expectation under Hardy-Weinberg equilibrium. The genotype frequencies deviate significantly from the expectation under Hardy-Weinberg equilibrium. The genotype frequencies do not deviate significantly from the expectation under Hardy-Weinberg equilibrium. The population does not meet any of the assumptions of Hardy-Weinberg equilibrium. The population meets all of the assumptions of Hardy-Weinberg equilibrium.
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