Question

In a population, genes A and B, each with two alleles, are linked. There are 4 individuals with haplotype "AB", 2 with 'ab' and 2 with 'ab' and 2 with 'aB'. Calculate linkage disequilibrium (D), where D = P(AB) - P(A)P(B) (where P(AB) is the frequency of that haplotype, and p(A) and P(B) are the frequencies of those individual alleles

Name: in a population genes a and b each with two alleles are linked there are 4 individuals with haplotype ab 2 with ab and 2 with ab and 2 with ab calculate linkage disequilibrium d where d pab 74998
Uploaded: 2023-05-01T05:58:14-08:00
Duration: 6 min 47 s
Channel: Supreeta N
Description: in a population genes a and b each with two alleles are linked there are 4 individuals with haplotype ab 2 with ab and 2 with ab and 2 with ab calculate linkage disequilibrium d where d pab 74998

          In a population, genes A and B, each with two alleles, are
linked. There are 4 individuals with haplotype "AB", 2 with 'ab'
and 2 with 'ab' and 2 with 'aB'. Calculate linkage disequilibrium
(D), where D = P(AB) - P(A)P(B) (where P(AB) is the frequency of
that haplotype, and p(A) and P(B) are the frequencies of those
individual alleles

Added by Karen B.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Supreeta N

05/01/2023

Step 1

There are a total of 4 + 2 + 2 + 2 = 10 individuals in the population. The frequency of each haplotype is: - P(AB) = 4/10 = 2/5 - P(aB) = 2/10 = 1/5 - P(Ab) = 2/10 = 1/5 - P(ab) = 2/10 = 1/5 Now, we need to find the frequencies of each allele: - P(A) = (P(AB) + Show more…

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In a population, genes A and B, each with two alleles, are linked. There are 4 individuals with haplotype "AB", 2 with 'ab' and 2 with 'ab' and 2 with 'aB'. Calculate linkage disequilibrium (D), where D = P(AB) - P(A)P(B) (where P(AB) is the frequency of that haplotype, and p(A) and P(B) are the frequencies of those individual alleles