In March 2014, a deadly outbreak of a hemorrhagic fever erupted in Guinea, but the causative agent was unknown. Genetic sequences of three patients were obtained, and were compared in a phylogenetic tree with representatives of filoviruses. Based on the information in this phylogenetic tree, write the full and exact name of the virus the unknown isolates are most closely related to. 1 0.1 1 A 1 Sudan ebolavirus 0.99 Reston ebolavirus Lloviu cuevavirus Marburg 2 marburgvirus Ravn virus Marburg marburgvirus Bundibugyo ebolavirus Tai Forest ebolavirus Zaire ebolavirus Unknown virus isolate 1 Unknown virus isolate 2 Unknown virus isolate 3
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You are studying the source of new virus that has recently infected humans. You suspect that the virus was transferred from other primates (they exhibit a similar infection), specifically chimpanzees, gorillas, or orangutans. You sample blood from several infected humans and sequence some viral genes. You then build a phylogenetic tree with the human sequences and all the known strains from each primate. Draw a hypothetical phylogenetic tree that would suggest that the virus came from gorillas, and this transfer occurred twice independently. Label chimp sequences (c), gorilla (g), orangutans (o), and humans (h).
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