In one family, the genetic disorder, Nail Patella, was found to be linked to the ABO blood type locus. In what way is this information helpful to geneticists? A It narrows down what part of the genome the gene responsible for Nail Patella could be found. B It identified the gene responsible for Nail Patella. C It shows that the ABO blood locus causes Nail Patella. D It demonstrates that the gene for Nail Patella is paternally inherited. E It does not provide any of this information.
Added by Lisa C.
Close
Step 1
Step 1: Restate the fact — in this family, Nail Patella is reported to be linked to the ABO blood type locus. Show more…
Show all steps
Your feedback will help us improve your experience
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Does this family provide evidence of genetic linkage between nail-patella syndrome and ABO blood group? No, there is no genetic linkage between NPS and ABO blood group. Yes, NPS appears to segregate with blood type A in this pedigree, indicating genetic linkage between these traits. Yes, NPS appears to segregate with blood type B in this pedigree, indicating genetic linkage between these traits. Why or why not? The frequency of recombinant progeny is more than 10%. The frequency of recombinant progeny is less than 10%. The frequency of recombinant progeny is less than 50%.
Dominador T.
Genes for Nail-patella syndrome (N) and the ABO blood type (I) are 10 map units apart on chromosome 9. Greg and Susan each have Nail-patella syndrome (autosomal dominant trait that causes absent or underdeveloped nails and painful arthritis). Greg has type A blood and Susan has type B blood. Greg's mother has NP and type A blood, and his father has normal nails and type O blood. Susan's mother has NP and type O blood, and her father has normal nails and blood B. What is the probability that their child has Nail-patella syndrome and type O blood? Greg Susan Phenotype nail-patella syndrome, type A blood nail-patella syndrome, type B blood Genotype NnIA NnIB Allele configuration N IA / n i N i / n IB Gametes: sperm frequency oocytes Parental N IA 45% N i n i 45% n IB Recombinants N i 5% N IB n IA 5% n i N = nail-patella syndrome n = normal
Adi S.
The figure that follows shows the pedigree of a family in which a completely penetrant, autosomal dominant disease is transmitted through three generations, together with microarray analysis of each individual for a biallelic SNP locus (the alleles are $C$ and $T$ ). a. Do the data suggest the existence of genetic linkage between the SNP locus and the disease locus? If so, what is the estimated genetic distance between the two loci? b. Calculate the maximum Lod score for linkage between the SNP and the disease locus for this pedigree. What does this value of the Lod score signify?
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD