In the higher energy chair conformation, which of the following cyclohexanes experiences the greatest 1,3-diaxial strain? A) B) C) D) HH H${\rm _3}$C H${\rm _3}$C CH${\rm _3}$ CH${\rm _3}$ CH${\rm _3}$ CH${\rm _3}$ H CH${\rm _3}$ E) I don't know
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Step 1: Recall what 1,3‑diaxial strain is — an axial substituent on C‑1 of a cyclohexane sterically clashes with the two axial hydrogens on C‑3 and C‑5; the larger the substituent, the larger the 1,3‑diaxial steric penalty when it is axial. Show more…
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