00:01
Not to answer this question, let's talk about insulin.
00:03
It says insulin does not, and let's look at the options.
00:05
Option a says, insulin does not increase glucose uptake by the liver.
00:11
And this is true, because remember that insulin is going to be useful for the uptake of glucose by insulin -dependent tissues.
00:20
For example, the skeletal muscle and the adipose tissue.
00:30
Okay, normally these tissues here don't have glucose receptors expressed on their surface.
00:36
But when insulin binds to the receptors, when insulin binds to its receptor on the surface of these tissues here, it is going to allow the expression of glucose transporters on the surface of these tissues, and this is going to allow the uptake of glucose by these tissues.
00:58
Option bises get secreted when calcium increases in the cytosol of the beta cells on the pancreas.
01:03
And this option is also true because, or i'm sorry, this is false, okay? because remember that if this is your beta cell of pancreas, normally your beta cell of pancreas has vesicles containing insulin.
01:18
Insulin and some other molecules, for example, zinc and also amyline.
01:23
So in order for these vesicles to develop exocytosis like this and release the insulin out of the cell, you need calcium.
01:34
Okay, so practically calcium is going to be useful for these vesicles to develop exocytosis...