Question

Isocitrate dehydrogenase is found only in the mitochondria, but malate dehydrogenase is found in both the cytosol and mitochondria. What is the role of cytosolic malate dehydrogenase? (multiple choices) a. It plays a key role in the conversion of mitochondrial pyruvate to cytosolic oxaloacetate to fuel gluconeogenesis. b. It plays a key role in the transport of reducing equivalents across the inner mitochondrial membrane via the malate-aspartate shuttle. c. It delivers the reducing equivalents from NADH through FAD to ubiquinone and thus into Complex III. d. It catalyzes the oxidation of malate to oxaloacetate, coupled to the reduction of NAD+ to NADH, in the last reaction of the citric acid cycle. e. It is a point of electron entry into the mitochondrial respiratory chain.

          Isocitrate dehydrogenase is found only in the mitochondria, but malate dehydrogenase is found in both the cytosol and mitochondria.

What is the role of cytosolic malate dehydrogenase? (multiple choices)

a. It plays a key role in the conversion of mitochondrial pyruvate to cytosolic oxaloacetate to fuel gluconeogenesis.
b. It plays a key role in the transport of reducing equivalents across the inner mitochondrial membrane via the malate-aspartate shuttle.
c. It delivers the reducing equivalents from NADH through FAD to ubiquinone and thus into Complex III.
d. It catalyzes the oxidation of malate to oxaloacetate, coupled to the reduction of NAD+ to NADH, in the last reaction of the citric acid cycle.
e. It is a point of electron entry into the mitochondrial respiratory chain.

isocitrate dehydrogenase is found only in the mitochondria but malate dehydrogenase is found in both the cytosol and mitochondria what is the role of cytosolic malate dehydrogenase multiple 46356

Added by Michael S.

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