00:01
Now let us see which are the incorrect statements given in the question.
00:06
Now first statement is given about isinicazid.
00:17
And this is also called as isinicotinic acid hydrazide, which is nothing but i -n -h.
00:26
Now this is generally given as an antibiotic to treat tuberculosis.
00:31
So this is generally to treat tuberculosis.
00:39
Okay.
00:39
Now, this generally inhibits the mycolic acid synthesis and this was studied and proved by using the cell extracts from both inh sensitive and resistant strains of mycobacterium.
00:53
Now, here it says that this is inhibiting the synthesis of mycolic acid and mycloplasm.
01:01
Now, this is not the correct statement because mycoplasma is not included in the acid fastic.
01:14
Bacterial genus so they do not have mycolic acid so there is no mycolic acid hence there is also no synthesis of mycolic acid and also it lacks cell wall okay so mycobacterium included in the acid fasting bacterial genus and they have high level of mycolic acid in the cell wall so this can inhibit the synthesis of mycolic acid only in mycobacterium but not in mycoplasma now understanding the second statement, beta -lactam antibiotics inhibit 70s ribosomes is also incorrect because these inhibit bacteria by binding covalently to pencillin binding pencillin.
02:05
So talking about beta -lactam antibiotics, we see that they are binding covalently to pencilin binding pencilin proteins.
02:41
Enzymes.
02:42
So they bind to these pencyline binding pencillin proteins enzymes and these are involved in the process of formation of peptidoglycan which helps to form cell wall in bacteria.
02:54
So any alteration in pencillin binding pencillin will lead to beta lactam antibiotics resistant.
03:00
So generally canamysin and togramicin are one of the most commonly used aminoglycocytes antibiotics which generally inhibit 70s ribosomes.
03:10
So this is also the incorrect statement.
03:13
Now let's look at the third statement...