KEY: A= tertiary structure B= primary structure C= secondary...

KEY: A= tertiary structure B= primary structure C= secondary structure D= quaternary structure E= none of these Several proteins are described below. Match the letter that corresponds to the class of protein structure that is being described: 1. A protein has a molecular weight of 68 kDa (68,000 g/mol) 2. A Protein is composed of six identical polypeptide subunits (a homohexamer) 3. A protein requires a vitamin cofactor to function 4. A protein is entirely alpha-helical 5. A protein has a red color in solution 6. A protein has the amino acid sequence Glu-Ser-Lys-Met_Leu-Thr-Pro-Leu-Arg 7. A protein has one beta sheet and one alpha helix that together adopt the ubiquitin-like domain fold 8. A protein functions as a heterodimer 9. A protein contains an SH2 domain followed by a PTD domain 10. A protein has an isoelectric point of 6.2

Transcript

00:01 So the question gave you four different, well, actually five different cases.

00:06 A stand for tertiary structure, b stand for primary structure, c stands for secondary structure, d stand for quantum neural structure, it stands for none of these.

00:16 So the question gave you 10 different events.

00:21 So match the latter that corresponding to the class of protein structure that is being described.

00:28 So first of all, i want to talk a little bit about, each of the structure's definition.

00:33 So for the primary structure, it usually means the sequence of amino acid.

00:41 And somehow all the aspects that relate to the amino acid sequence such as the mutation or the molecular weight.

00:51 And these are all defined as the primary structure of the protein.

00:55 Basically, anything somehow relate to the sequence of amino acid.

01:01 Then we talk about secondary structure.

01:06 The secondary structure means the local folding structure due to the interaction between the atoms of the backbones.

01:16 So basically there are two different secondary structure, usually beta sheet and the other is alpha helix.

01:24 These are the hydrogen bond that in between the backbone of amino acid.

01:32 Now, what is the tertiary structure? when we talk about tertiary structure of protein, we're talking about the three -dimensional structure that, you know, form due to the interaction between the amino acid side chains, so r -groups.

01:48 So sometimes they have hydrogen bond, sometimes they have hydrophobic interaction or disulfide bond.

01:55 All these interaction between the side chain or r -group of different amino acid, they will form.

02:02 A three -dimensional structure of the polypeptide.

02:07 So this is defined as the tertiary structure.

02:11 That basically means a protein are being folded into a certain shape because of interaction between amino acids.

02:20 And of course, the last one is quantum neural structure.

02:23 This is defined as basically multiple polypeptide subunit.

02:29 They come together to form certain interaction or structures.

02:35 So basically, when it involves multiple polypeptide, multiple subunit, then this is defined as the quantumary structure.

02:44 Now, let's take a look at each of those descriptions.

02:49 So i'm only using the keywords here.

02:52 So first one, the molecular weight of 68 kilodont.

03:00 So this obviously relate to the primary structure.

03:05 The primary structure means the amino acid sequence.

03:10 So the molecular weight of protein is depend on the amino acid sequence.

03:15 So this is going to be b.

03:21 Homohexamer.

03:22 This is the second description.

03:25 It's a six identical polypeptide subunits...

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