Label (and draw if needed) the following players in a replication bubble: • Template strands • Helicase • DNA Polymerase • Primase • Replication forks • Origin of replication • Lagging strands • Leading strands • Okazaki Fragments (label the order in which they were built) direction of fork movement Other good things to do: • Indicate where you would find RNA and DNA in the Okazaki fragments • Label the 5' and 3' ends of strands • Show the molecular events that would lead telomeres toget shorter with each round of replication
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Step 1: Label the players in the replication bubble: - Template strands - Helicase - DNA Polymerase - Primase - Replication forks - Origin of replication - Lagging strands - Leading strands - Okazaki Fragments (label the order in which they were built) Show more…
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Draw a DNA replication bubble. Label each strand (every and all strands) with its 5' and 3' ends. Label all lagging and leading strands. Label all Okazaki fragments. Label the primer and what kind of nucleic acid it is. Label all directions that the bubble is opening.
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Draw in the other half of the replication bubble on the figure below to demonstrate that bidirectional DNA replication is occurring. Label the following: RNA primers, leading and lagging strands, Okazaki fragments, and 5' and 3' ends of all DNA fragments, including the other half of the replication bubble that you drew.
Draw a molecule of DNA undergoing eukaryotic linear replication. On your drawing, identify (a) origin of replication, (b) polarity (5' and 3' ends) of all template and newly synthesized strands, (c) leading and lagging strands, (d) Okazaki fragments, and (e) locations of primers.
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