00:01
Okay, in order to answer this question, let's talk about cell signaling.
00:03
You remember that this is your cell membrane, there are receptors that can be either located here on the cell surface or inside of a cell.
00:16
Okay? and well, and you have also ligands.
00:19
Ligants are those molecules that combine to the receptors and cause a biological response.
00:24
So what is going to be the property of this, or depending on what property of this ligand is going to account for the receptors or for the presence of the receptors here on the cell surface or inside of a cell.
00:36
And it is going to be, for example, if this ligand is lipid soluble or the solubility of this ligand, if this ligand is lipid soluble, then it is going to be able to cross a cell membrane.
00:50
So it is not going to require these receptors here because they can diffuse the cell membrane possibly.
00:55
So the receptors are going to be found here.
00:58
One example of these ligands is aldosterone.
01:00
Aldosterone is a hormone made of cholesterol, so it is going to be able to diffuse this lipid by layer, that is a membrane, and bind to receptors inside of a cell.
01:11
And what happens if this hormone is not lipid soluble? okay, for example, epinephrine...