00:01
Which of these is least likely to cause an immune reaction? the cell wall, the outer membrane, the flagellum, or the ribosome.
00:10
So the bacterium breaks down, its components are now in the blood, and we're going to potentially have an immune reaction to some of these.
00:18
So the innate immune response has a lot of different receptors, like toll -like receptors, nord -like receptors, and these detect pathogen -associated patterns.
00:30
These are called pamps.
00:34
Pathogen -associated molecular patterns.
00:38
So generally, these are things that you would never find in the human body, but you would find in a potential pathogen.
00:45
For example, if we start the cell wall, the cell wall is made of peptidoglycan.
00:50
We don't produce peptidoglycan, so it is a possible because it's something that bacteria have, but we don't.
01:01
So if the immune system reacts to it, it's not going to be.
01:03
Reacting to self, it's going to be reacting to something foreign.
01:10
The outer membrane, for the same reason, the outer membrane is going to have bacterial proteins on it, which are very good targets for the innate immune system...