Match each of the mutagens with a the most applicable mutation mechanism description Makes pyrimidine dimers by making a bond between adjacent pyrimidines, thus interfering with the normal base pairing between the complementary DNA strands. - Results in double stranded DNA breaks - Substitutes for a normal base in DNA resulting in mispairing during DNA replication. - Adds chemical groups to to guanine thus altering its pairing properties to pair with thymine - Planer molecules that mimic base pairs and slip themselves in between the stacked nitrogen bases at the core of the DNA double helix. These agents can cause an insertion or deletion of nucleotide pairs. A. UV radiation B. Alkylating agent C. Ionizing Radiation D. Base Analog E. Intercalating agent
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Step 1: UV radiation makes pyrimidine dimers by making a bond between adjacent pyrimidines, thus interfering with the normal base pairing between the complementary DNA strands. Show more…
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What type of mutations does EMS cause? a. Mismatched bases d. Insertions and deletions c. Chromosome breaks d. Pyrimidine dimers e. Deamination of cytosine In bacteria, which of the following is true? a. Repressors bind to the DNA in between the first and second gene of the operon b. Repressors bind to the DNA just upstream of the promoter c. Activators bind to the DNA in between the first and second gene of the operon d. Activators bind to the DNA in between the promoter and the first gene of the operon e. Activators bind to the DNA just upstream of the promoter f. None of the above Which of the following is true about Mismatch DNA repair systems? a. the mismatch repair system removes nucleotides, then replaces them with the correct nucleotides and seals the nick in the backbone. b. The mismatch repair system replaces the mismatched base on the methylated strand c. the mismatch repair system works after DNA replication to fix errors not caught by DNA polymerase d. all of the above e. none of the above
Sri K.
Matching: Match the mutation type with its term (5 pts) Base Pair Substitution UV Radiation Transposons Frameshift When protein is changed due to deletion or insertion Type of mutation caused during DNA replication or repair A harmful environmental agent that causes DNA damage When one nucleotide is changed for another E: Jumping genes that can insert themselves into the genome Spontaneous
Adi S.
Match the substance to its function Prevents supercoiling/Overwinding of the DNA Unwinds and separates the double-stranded DNA Adds a short piece of complementary RNA nucleotides Copies DNA and adds complementary DNA nucleotides Prevents DNA strands from connecting Links together short segments of DNA Found only in the lagging strand What chromosomes are made of Nucleosomes B. Topoisomerase C. Ribosome D. Nuclease E. RNA polymerase F. Helicase G. DNA Polymerase H. DNA and Proteins The proteins found in chromosomes Codon DNA wrapped around proteins Responsible for making mRNA Okazaki Fragments K. Anticodon The site of translation L. DNA Ligase M. Histones Cuts DNA for mutation repair A triplet of nucleotides on mRNA N. Primase O. Single Strand Binding Proteins Triplet of nucleotides on tRNA
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