Match the agent to its mechanism of action. Phenols lodine Carbon dioxide Nisin [Choose] [Choose] inhibits cell wall synthesis lowers intracellular pH destabilizes cellular macromolecules denature proteins and disrupt membrane integrity [Choose]
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Match the description of the different chemical methods of microbial control on the left to its term on the right. surfactants: emulsify and solubilize particles clinging to a surface phenol: destroys bacterial cells by disrupting cell membrane bacteriocin: proteins produced by one bacterium that inhibits another triclosan: used in mouthwash and toothpastes quat: used to sterilize medical implants heavy metal: CO2 with gaseous and liquid properties supercritical fluid: used to sterilize medical implants chlorhexidine: destroys bacterial cells by disrupting cell membrane soap: emulsify and solubilize particles clinging to a surface CO2: with gaseous and liquid properties
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Which method of microbial control does not rely on denaturing proteins and/or disrupting the integrity of the cell membrane? - Treatment with iodophors - Treatment with alcohols - Lyophilization - Autoclaving Which substance would be most useful as an antiseptic? - Iodine - Chlorine - Boiling - Ethylene oxide Halogens denature protein by affecting which bonds? - Hydrogen bonds - Peptide bonds - Disulfide bonds - Ionic bonds Selective toxicity is the ability of a chemical or drug to kill a microorganism without harming its host. Which of the following antibiotics shows low selective toxicity? - Isoniazid - Penicillin - Neomycin - Rifamycin
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Match the descriptions and antimicrobial agents to the appropriate type of germicide to test your knowledge of alcohols, halogens, phenolic compounds, and quaternary ammonium compounds as germicidal chemicals. Halogens Solutions can be used chlorine as antiseptics or disinfect instruments and surfaces without leaving residue: Common disinfectant which oxidizes proteins and other cell components. Carbolic acid Quaternary Ammonium Compounds Compound reacts with membranes to destroy many vegetative bacteria and enveloped viruses. These compounds are ineffective against mycobacteria, naked viruses, and Pseudomonas species. Alcohols Aqueous solutions which can kill vegetative bacteria and fungi but not bacterial endospores or naked viruses: Ethanol or isopropanol Germicidal agent which can leave an antimicrobial residue after use. Cationic detergent which can be safely used on food preparation surfaces. Phenolic Compounds
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