00:01
Okay, in order to answer this question, let's talk about prions.
00:07
Prioryons are practically misfolded proteins.
00:12
Okay, misfolded proteins.
00:16
In our cells, we normally have some proteins called prion -related proteins.
00:28
These proteins are normally produced by our cells.
00:31
Okay, they are normally produced by our cells.
00:33
It means even when we don't have any disease.
00:37
So normally when a gene produces a protein in our cells, in our normal and healthy cells, it is arranged in a helical arrangement.
00:50
Okay, and this is called alpha helical arrangement.
00:59
This is what normally happens as after we produce a protein, okay? and this occurs for this pyrom elect proteins.
01:05
And what happens in pyons? well, when there is misfolding of these proteins, they are.
01:13
Not going to arrange in this alpha helical arrangement, but instead of this they are going to arrange in a beta pleaded arrangement...