Question

A mother notices her female child (age 4) is bruising easily, sometimes without a known cause. Her child is crying a lot and complaining her ?legs hurt.? She has also not been as active as usual in the past month. In the past 48 hours the child has developed a fever and seems very fatigued. Unable to break the fever, the mother takes her child to the pediatrician. 1. Based on the age of this patient and the presenting symptoms, would you predict an acute or chronic condition? 2. Why do you think the child has pain in her legs? 3. Does this align with your answer to #1? 4. Why might the child be bruising and feeling tired? The pediatrician orders a CBC. Results are as follows: RBC count = 2.1 x 1012/L Hgb = 8.1 g/dL Hct = 24% WBC count = 38 x 109/L Plt count = 49 x 109/L Smear shows low neutrophils, high lymphocytes, and 10% blasts present 5. Based on these lab findings, is this an acute or chronic condition? 6. Taking all information thus far into account, is this likely AML or ALL? 7. List the three major ALL WHO classifications. 8. Using Box 11.1, what are the two next steps needed to diagnose this patient?

          A mother notices her female child (age 4) is bruising easily, sometimes without a known cause. Her child is crying a lot and complaining her ?legs hurt.? She has also not been as active as usual in the past month. In the past 48 hours the child has developed a fever and seems very fatigued. Unable to break the fever, the mother takes her child to the pediatrician.

1. Based on the age of this patient and the presenting symptoms, would you predict an acute or chronic condition?

2. Why do you think the child has pain in her legs?

3. Does this align with your answer to #1?

4. Why might the child be bruising and feeling tired?

The pediatrician orders a CBC. Results are as follows:
RBC count = 2.1 x 1012/L
Hgb = 8.1 g/dL
Hct = 24%
WBC count = 38 x 109/L
Plt count = 49 x 109/L
Smear shows low neutrophils, high lymphocytes, and 10% blasts present

5. Based on these lab findings, is this an acute or chronic condition?

6. Taking all information thus far into account, is this likely AML or ALL?

7. List the three major ALL WHO classifications.

8. Using Box 11.1, what are the two next steps needed to diagnose this patient?

A mother notices her female child (age 4) is bruising easily, sometimes without a known cause. Her child is crying a lot and complaining her ?legs hurt.? She has also not been as active as usual in the past month. In the past 48 hours the child has developed a fever and seems very fatigued. Unable to break the fever, the mother takes her child to the pediatrician.

1. Based on the age of this patient and the presenting symptoms, would you predict an acute or chronic condition?

2. Why do you think the child has pain in her legs?

3. Does this align with your answer to #1?

4. Why might the child be bruising and feeling tired?

The pediatrician orders a CBC. Results are as follows:
RBC count = 2.1 x 1012/L
Hgb = 8.1 g/dL
Hct = 24%
WBC count = 38 x 109/L
Plt count = 49 x 109/L
Smear shows low neutrophils, high lymphocytes, and 10% blasts present

5. Based on these lab findings, is this an acute or chronic condition?

6. Taking all information thus far into account, is this likely AML or ALL?

7. List the three major ALL WHO classifications.

8. Using Box 11.1, what are the two next steps needed to diagnose this patient?

Added by Eric L.

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