1. Name the gene that is responsible for the development of testes (i.e., differentiation of the gonadal ridges into testes) in the genetic (XY) male? 2. Name the substance (hormone) secreted by Sertoli cells that is responsible for degeneration of the female (paramesonephric or Mullerian) duct in the male fetus? 3. Name the male and female structures that form from the genital tubercle and labioscrotal swelling. 4. What happens to a genetic male fetus if the testes are not producing testosterone? 5. What happens to a genetic male fetus if the testes are not producing MIH?
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The gene responsible for the development of testes in the genetic (XY) male is called SRY (Sex-determining Region Y). Show more…
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The sex-determining region of the Y chromosome (SRY) in humans codes for the SRY protein, also known as the testis-determining factor. Which of the following is true about the testis-determining factor? (1) It causes the Wolffian ducts to disappear. (2) It masculinizes the external genitalia by binding to androgen receptors. (3) Some of the answers are correct. (4) It catalyzes the transformation of androgens to estrogens. (5) It causes the medulla of the bipotential gonads to turn into testes.
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