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A new antibiotic is discovered that is highly effective against both gram-negative and gram-positive bacteria but the exact mechanism it uses to halt bacterial growth is not known. It is run through a battery of tests comparing it to a control culture without any antibiotics. The new antibiotic has no effect on the incorporation of radioactive uracil or thymine. And no DNA is detected in the supernatant. But it is severely impaired in the incorporation of radioactive methionine. What process is it likely affecting? translation DNA replication cell wall synthesis a metabolic process transcription Question 32 Mycoplasma pneumoniae is an "atypical" bacterium that commonly causes infections of the respiratory system such as pneumonia. It is a pleiomorphic, aerobic bacterium that takes 10-14 days for observable colonies to form on agar media. Which of the following antibiotics would you use to combat this infection? Penicillin Vancomycin Ciprofloxin Clavulanic acid Metrinidozole

          A new antibiotic is discovered that is highly effective against both gram-negative and gram-positive bacteria but the exact mechanism it uses to halt bacterial growth is not known. It is run through a battery of tests comparing it to a control culture without any antibiotics. The new antibiotic has no effect on the incorporation of radioactive uracil or thymine. And no DNA is detected in the supernatant. But it is severely impaired in the incorporation of radioactive methionine. What process is it likely affecting?
translation
DNA replication
cell wall synthesis
a metabolic process
transcription
Question 32
Mycoplasma pneumoniae is an "atypical" bacterium that commonly causes infections of the respiratory system such as pneumonia. It is a pleiomorphic, aerobic bacterium that takes 10-14 days for observable colonies to form on agar media. Which of the following antibiotics would you use to combat this infection?
Penicillin
Vancomycin
Ciprofloxin
Clavulanic acid
Metrinidozole

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A new antibiotic is discovered that is highly effective against both gram-negative and gram-positive bacteria but the exact mechanism it uses to halt bacterial growth is not known. It is run through a battery of tests comparing it to a control culture without any antibiotics. The new antibiotic has no effect on the incorporation of radioactive uracil or thymine. And no DNA is detected in the supernatant. But it is severely impaired in the incorporation of radioactive methionine. What process is it likely affecting?
translation
DNA replication
cell wall synthesis
a metabolic process
transcription
Question 32
Mycoplasma pneumoniae is an "atypical" bacterium that commonly causes infections of the respiratory system such as pneumonia. It is a pleiomorphic, aerobic bacterium that takes 10-14 days for observable colonies to form on agar media. Which of the following antibiotics would you use to combat this infection?
Penicillin
Vancomycin
Ciprofloxin
Clavulanic acid
Metrinidozole

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Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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Solved by Expert Farhan Anwar

02/27/2023

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Since no DNA is detected in the supernatant, it is not affecting cell wall synthesis. The antibiotic is severely impaired in the incorporation of radioactive methionine, which is an amino acid. This suggests that the antibiotic is affecting a process involving Show more…

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A new antibiotic is discovered that is highly effective against both gram-negative and gram-positive bacteria but the exact mechanism it uses to halt bacterial growth is not known. It is run through a battery of tests comparing it to a control culture without any antibiotics. The new antibiotic has no effect on the incorporation of radioactive uracil or thymine. And no DNA is detected in the supernatant. But it is severely impaired in the incorporation of radioactive methionine. What process is it likely affecting? translation DNA replication cell wall synthesis a metabolic process transcription

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00:01 Okay, so for this first question, an antibiotic is discovered highly effective against gram positive gram -negative bacteria, but the mechanism is not known.

00:09 Right, so we know that this antibiotic has no effect on the incorporation of radioactive ursul or radioactive thymine.

00:18 No dna is detected on the supernatins, but it is severely impaired in the incorporation of radioactive methyanine.

00:27 So basically what this does is this antibiotic prevents the uptake of methyanine.

00:41 That's what the radioactive methanine is telling us.

00:43 So basically it inhibits methionine uptake.

00:47 So if it's preventing methionine uptake, what is it stopping? it's stopping translation.

01:04 So why is it stopping translation? what is methionine use for? remember, the start codon, a -u -g -g -e -g.

01:09 Codes for, so does it start codon, for translation, codes for methyony.

01:19 If there's no methyonyne, translation cannot start.

01:23 Okay.

01:25 So, next question.

01:28 Mycoplasma pneumonia is an atypical bacterium commonly causes infections in the respiratory system known as, such as pneumonia.

01:35 Makes sense.

01:36 It is pleomorphic.

01:37 Pleomorphic means can have different shapes.

01:53 So what i mean by that is you can have a bacillus or you can have a more coxie -like structure, okay? and it can switch between these two.

02:11 It's aeroic.

02:15 So pleomorphic aerobic.

02:18 Okay.

02:21 It takes 10 to 14 days to sea colonies on auger media.

02:25 What, which of the following antibiotics would you use to combat this? penicillin, vancomycin, syprofluoxin, clavulinic acid, or metronidazole.

02:35 So, oh, and also call this, let's go up a bit, make sure write down atypical.

02:45 Right, so what are our drug options? we have penicillin.

02:54 It targets peptideoglycan synthesis.

03:03 It's an atypical organism.

03:05 And it's mycoplas, which means not only does it have.

03:12 Have among its cell wall, it does have peptid glycate, but also has mycolic acid, which can affect penicillin sensitivity.

03:21 Vancomycin, also cell wall related...

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