No molecule x present A A A A Site 1 Site 2 Low concentrations of molecule x A A A A Site 1 Site 2 High concentrations of molecule x X A A A A Site 1 Site 2 When no molecule X is present, can the transcription factor A bind to either site on the DNA? [ Select ] When there are low levels of molecule X, transcription factor A-X is able to bind to site 1. What can you tell about the affinity of transcription factor A-X complex for site 1 vs. site 2? [ Select ] Which site requires a much larger concentration of the transcription factor A-X complex in order to bind? [ Select ]
Added by Jared W.
Close
Step 1
Step 1: When no molecule X is present, the transcription factor A can bind to either site on the DNA. Show more…
Show all steps
Your feedback will help us improve your experience
Md.Daniyal Arshad and 74 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Transcription factor binding Transcription factors are proteins that bind to specific sequences of DNA and regulate transcription of genes (i.e., turn "on" and "off" the ability of the cell to make mRNA copies). Consider a particular transcription factor for which there are N possible binding sites along the DNA. Assume there are NTF identical copies of this transcription factor in the cell. a. How many different binding arrangements are there of these NTF transcription factors? b. If transcription factor – DNA binding has an energy ΔE=-16 kJ/mol, determine the free energy change associated with 10 transcription factors binding to a piece of DNA which possesses 15 possible binding sites. c. How does this free energy change compare with the free energy of ATP hydrolysis?
Sri K.
How do eukaryotic transcription factors exert their effects on transcription when their binding sites can be thousands of base pairs away from the promoter? After binding to the site, the regulatory protein releases the DNA and is targeted to the polymerase via coactivator proteins. Regulatory proteins bind to the sequences and then slide along the DNA until they reach an RNA polymerase bound to a promoter. The DNA between the bound site and the polymerase-promoter complex loops out, increasing proximity. Once bound to the site, the regulatory protein catalyzes the formation of an effector molecule that then travels to and binds the polymerase. None of these answers is correct.
Jenny W.
A mutation within the promoter region can alter gene transcription. Describe how this can happen. a. Mutated promoters decrease the rate of transcription by altering the binding site for the transcription factor. b. Mutated promoters increase the rate of transcription by altering the binding site for the transcription factor. c. Mutated promoters alter the binding site for transcription factors to increase or decrease the rate of transcription. d. Mutated promoters alter the binding site for transcription factors and thereby cease transcription of the adjacent gene.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD