Nondisjunction (failure to separate) of sex chromosomes during human gamete formation may lead to individuals with sex chromosome trisomy. An individual with the sex chromosome trisomy of XXY may have resulted from nondisjunction occurring in (For each possibility below, write True or False and explain why): Meiosis I in the father's sperm production Meiosis II in the father's sperm production Meiosis I in the mother's egg production Meiosis II in the mother's egg production
Added by Kathleen O.
Step 1
If the sperm cell with two X chromosomes fertilizes a normal egg with one X chromosome, the resulting zygote will have an XXY karyotype. Meiosis II in the father’s sperm production: True Explanation: If nondisjunction occurs during meiosis II in the father's Show more…
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For each of the following nondisjunction events, explain whether or not they could have produced an individual with Klinefelter's syndrome (47, XXY). For each event, state which sex chromosomes would be present in the sperm and the egg. In each case, assume that meiosis has proceeded normally in the other parent. HINT: draw out each case. Remember that in meiosis in XY individuals, the X and Y chromosomes pair in Meiosis I. a) Nondisjunction in meiosis I in the mother. b) Nondisjunction in meiosis II in the mother. c) Nondisjunction in meiosis I in the father. d) Nondisjunction in meiosis II in the father.
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