Nosocomial infection caused by Methicillin-resistant Staphylococcus aureus (MRSA), has been a challenge especially in managing antibiotic resistance. Scientists have been actively searching for new antibiotics to overcome MRSA. In a study, an antibiotic Norveex A is examined for its antimicrobial properties on Staphylococcus sp. The bacterial growth conditions are tabulated as below: Concentration of Norveex A (µg/ml) | Time 0 h | Time 1 h | Time 2 h | Time 3 h | After removal of Norveex A | Time 4 h ---|---|---|---|---|---|--- 10 | + | + | + | + | | + 20 | + | + | + | + | | + 40 | + | + | - | - | | - 80 | + | - | - | - | | - 160 | + | - | - | - | | - Positive sign indicates bacterial growth while negative sign indicates no bacterial growth.
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Vancomycin-Resistant Staphylococcus aureus – Delaware, 2015 In April 2014, a chronic infection on the toe of a 67-year-old woman was noted during an examination. The woman was being treated in a Delaware hospital for diabetes mellitus, along with end-stage renal disease that required hemodialysis. Evaluation of the wound in August and October revealed the presence of methicillin-resistant Staphylococcus aureus (MRSA), a strain of the bacterium resistant to all the drugs commonly used to treat staphylococcal infections. What strategies could be employed to prevent the spread of VRSA if a healthcare worker is found to be infected with the bacterium? Why are patients with chronic conditions (diabetes, kidney failure, cancer) at greater risk of developing infections with drug-resistant organisms like VRSA?
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