Old erythrocytes are broken down and degraded in the [Select] The globins are hydrolyzed into amino acids, while the heme pigment is first converted to [Select] Macrophages then convert this to [Select] and travel through the blood bound to albumin proteins. The [Select] takes this out of the blood and puts it into bile. When the bile is released into the [Select] [Select] bacteria convert this substance to which gives the brown color of feces.
Added by Jared P.
Close
Step 1
Step 1: Old erythrocytes are broken down in the liver. Show more…
Show all steps
Your feedback will help us improve your experience
Keerti J and 96 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
The destruction and recycling of erythrocytes take place in the following steps: Put them in the right order: i) Globin is metabolized into amino acids which are then released into the circulation ii) Old erythrocytes become rigid and fragile; and their hemoglobin begins to degenerate iii) Dying erythrocytes are engulfed by macrophages iv) Heme and globin are separated v) Heme is degraded to yellow pigment called bilirubin and secreted into the intestines as bile vi) Intestines metabolize bilirubin into urobilinogen which leaves the body
Keerti J.
A patient asks you about the fate of used-up red blood cells. You explain that indeed erythrocytes have a lifespan of about 100-120 days and that after that, all of the following will occur except: - They become trapped in the liver, which is the RBC graveyard, where the heme portion and the globin portion of the hemoglobin are reunited. - RBCs become old and lose their flexibility, becoming rigid and fragile. - The heme portion of the hemoglobin splits from the globin and eventually leaves the body as a brown pigment called sterobilin. The globin part of hemoglobin is broken down into amino acids, which are released into circulation. - The used-up RBCs are engulfed and destroyed by macrophages.
Adi S.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
200,000+
Students learning Biology with Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD