Question

Oncogenes, Tumor-suppressor genes, and tumors For each of the following situations, provide a plausible explanation for how it could lead to unrestricted cell division. Colon cancer cells often contain mutations in the gene encoding the prostaglandin E2 (PGE2) receptor. PGE2 is a growth factor required for the division of cells in the gastrointestinal tract. Adenovirus, a tumor virus carries a gene for the protein E1A, which binds to the retinoblastoma protein (Rb).

Name: oncogenes tumor suppressor genes and tumors for each of the following situations provide a plausible explanation for how it could lead to unrestricted cell division colon cancer cells often 65156
Uploaded: 2023-06-22T09:46:48-08:00
Duration: 4 min 58 s
Channel: Adi S
Description: oncogenes tumor suppressor genes and tumors for each of the following situations provide a plausible explanation for how it could lead to unrestricted cell division colon cancer cells often 65156

          Oncogenes, Tumor-suppressor genes, and
tumors
For each of the following situations, provide a plausible
explanation for how it could lead to unrestricted cell
division.
Colon cancer cells often contain mutations in the gene encoding
the prostaglandin E2 (PGE2) receptor. PGE2 is a growth factor
required for the division of cells in the gastrointestinal
tract.
Adenovirus, a tumor virus carries a gene for the protein E1A,
which binds to the retinoblastoma protein (Rb).

Added by Mary H.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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Solved by Expert Adi S

06/22/2023

Step 1

In the case of colon cancer cells with mutations in the gene encoding the PGE2 receptor, this could lead to unrestricted cell division if the mutated receptor is constantly active or has increased sensitivity to PGE2. This would result in continuous stimulation of Show more…

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Oncogenes, Tumor-suppressor genes, and tumors For each of the following situations, provide a plausible explanation for how it could lead to unrestricted cell division. Colon cancer cells often contain mutations in the gene encoding the prostaglandin E2 (PGE2) receptor. PGE2 is a growth factor required for the division of cells in the gastrointestinal tract. Adenovirus, a tumor virus carries a gene for the protein E1A, which binds to the retinoblastoma protein (Rb).