One way to cure cancer is for patients to take chemotherapy drugs such as vincristine and colchicine. These cancer drugs disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Exactly what mitotic structure is targeted by these drugs? What effect would they have on cell division? How does their action cure cancer?
Added by Jose M.
Step 1
Step 1: The mitotic structure targeted by chemotherapy drugs such as vincristine and colchicine is the microtubules. Show more…
Show all steps
Your feedback will help us improve your experience
Lainey Roebuck and 57 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Chemotherapy drugs such as vincristine (derived from Madagascar periwinkle plants) and colchicine (derived from autumn crocus plants) disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Exactly what mitotic structure is targeted by these drugs and what effect would that have on cell division?
Bryan V.
What occurs in a healthy cell when it becomes cancerous? In regard to mitosis, how does chemotherapy work to treat cancer? Why does the rate (fast or slow) of cell division impact our ability to effectively treat cancer with chemotherapeutic drugs? this is a pathophysiology course.
Adi S.
Chemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Exactly what mitotic structure do these drugs target, and what effect would that have on cell division? a. The drugs bind tubulin and inhibit the binding of spindle to the chromosome. This can arrest the cell cycle. b. The drugs bind the tubulin, which leads to an error in the chromosome separation. This could lead to apoptosis. c. The drugs bind the tubulin, thereby inhibiting their division in S-phase. This inhibits cell division. d. The drugs bind the spindle fiber and hinder the separation of chromatins. This promotes the division spontaneously.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD