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Ouabain is a highly toxic metabolite isolated from the bark of the ouabaio tree. If its toxicity is based solely on the complete inhibition of the Na+/K+ ATPase, how would this compound affect: (a) osmotic pressure of the cell; (b) cell volume; and (c) cotransport of glucose? Discuss the major osmolytes and molecular mechanisms involved in these effects.

          Ouabain is a highly toxic metabolite isolated from the bark of the ouabaio tree. If its toxicity is based solely on the complete inhibition of the Na+/K+ ATPase, how would this compound affect: (a) osmotic pressure of the cell; (b) cell volume; and (c) cotransport of glucose? Discuss the major osmolytes and molecular mechanisms involved in these effects.
        
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Biology for AP Courses
Biology for AP Courses
Julianne Zedalis, John Eggebrecht
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Ouabain is a highly toxic metabolite isolated from the bark of the ouabaio tree. If its toxicity is based solely on the complete inhibition of the Na+/K+ ATPase, how would this compound affect: (a) osmotic pressure of the cell; (b) cell volume; and (c) cotransport of glucose? Discuss the major osmolytes and molecular mechanisms involved in these effects.
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ouabain-is-a-highly-toxic-metabolite-isolated-from-the-bark-of-the-ouabaio-tree-if-its-toxicity-is-based-solely-on-the-complete-inhibition-of-the-nak-atpase-how-would-this-compound-effect-a-52725

Ouabain is a highly toxic metabolite isolated from the bark of the ouabaio tree. If its toxicity is based solely on the complete inhibition of the Na+/K+ ATPase, how would this compound affect: (a) osmotic pressure of the cell; (b) cell volume; and (c) cotransport of glucose? Discuss the major osmolytes and molecular mechanisms involved in these effects?

Madhur L.

ouabain-is-a-highly-toxic-metabolite-isolated-from-the-bark-of-the-ouabaio-tree-if-its-toxicity-is-based-solely-on-the-complete-inhibition-of-the-na-k-atpase-how-would-this-compound-effect-a-osmotic-p

Ouabain is a highly toxic metabolite isolated from the bark of the ouabaio tree. If its toxicity is based solely on the complete inhibition of the Na+ /K+ ATPase, how would this compound effect: (a) osmotic pressure of the cell; (b) cell volume; and (c) cotransport of glucose? Discuss the major osmolytes and molecular mechanisms involved in these effect

Aarya B.

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A researcher treats a solution containing animal cells with ouabain, a poisonous substance that interferes with the sodium–potassium ATPase embedded in the cell membrane, and the cell lyses as a result. Which of the following statements best describes ouabain’s effects? (A) $\quad$ Treatment with ouabain results in high levels of extracellular calcium. (B) Treatment with ouabain results in high levels of extracellular potassium and sodium. (C) Treatment with ouabain increases intracellular concentrations of sodium. (D) Treatment with ouabain decreases intracellular concentrations of sodium.


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Transcript

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00:01 Hello everyone in this question we'll be talking about ubein which is a toxic metabolite which is known to perform the inhibition of the sodium potassium atipase.
00:25 So the question here is how will it affect the osmotic pressure the cell volume and and the co -transport of glucose.
00:51 So the answer to this question is that we know that the function of the sodium potassium atopase is to export 3 sodium ions and import 2 potassium ions against 2 potassium ions against the gradient.
01:30 So here if the sodium potassium atypes is not working then it will result in the increase of the osmotic pressure as there will be accumulation of the sodium ions in the intracellular area and if we are talking about the cell volume, then we know that increase in the osmotic pressure will cause the water to enter the cell to maintain the osmolarity which will increase the cell volume if inhibited...
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