Part d genetic testing if jane and john want to have another...

Part D-Genetic testing If Jane and John want to have another child, they plan to see a genetic counselor to find out when it would be best to test for g put on a lactose- and galactose-free diet as soon as possible after birth. Even on this diet, affected individuals may still suffer fr women), late-onset cataracts, and early death. Which of the following tests would be most useful for Jane and John to have? View Available Hint(s) newborn screening (either assaying for the GALT enzyme or measuring excess galactose in the newborn's blood) no testing carrier screening of Jane and John (to identify whether either or both of them carry the allele for galactosemia) fetal chromosome analysis (examining fetal chromosomes for abnormalities as early as 11 weeks into the pregnancy) Submit

Transcript

00:01 In this question, we are going to talk about galactosemia.

00:05 Galactosemia, so it is an inherited disease.

00:10 It is an inherited disease, which means that it can transfer from the parent to the children.

00:25 So, it is an autosomal, autosomal recessive disease, autosomal recessive disease.

00:35 And if an individual is suffering from galactosemia, it means that his or her genotype, his or her genotype, both affected alleles, both affected alleles, they are present.

00:59 Because this disease, it is not expressed when the affected allele is present in the homozygous condition.

01:04 So, if an individual can be a carrier, individual can be a carrier of this disease, if one normal allele, it is present along with the affected allele.

01:22 So, if a carrier individual, a carrier individual for galactosemia, it is normal, but they can transfer the affected allele to the future generations, and affected children, affected children, they are born.

01:47 So, in the heterozygous condition of the genotype, the individual, it would be normal because in this condition, one normal allele and it is present, so it will dominate the affected allele.

02:09 After all, that would be a recessive allele.

02:12 So, in this question, we have option number b, which is a correct option.

02:19 It is a correct option and reason behind it that let us consider that both anika and jeremy, they are the carriers, both they are carriers of the galactosemia, which are normal, but they carry allele of the galactosemia in their genotype.

02:34 So, a, it is the normal allele and a, it is the galactosemia allele.

02:46 Galactosemia allele.

02:48 So, now to find the probability of a healthy child, who is not a carrier of galactosemia, a cross had been made, that is a a cross a a.

02:58 The gametes which are formed over here, it could be a a and then a a.

03:08 We will make a punnett square.

03:11 We have gametes a a, a a and a a...