4. You are studying patterns of divergence and polymorphism in the coding regions of Drosophila genes. In your samples you find 71 fixed and 106 polymorphic synonymous differences as well as 8 fixed and 13 polymorphic nonsynonymous differences. Carry out the McDonald-Kreitman's test of selection and interpret the results. (2pts)
Added by Luisa J.
Close
Step 1
In the first step, you want to identify the number of polymorphic differences in your data. Show more…
Show all steps
Your feedback will help us improve your experience
Madhur L and 76 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
3. Results: Let's assume in the F2 generation, the following results were obtained: Drosophila Dihybrid Cross-F2 Results Wildtype- 1750 Vesitigial- 535 Ebony-500 Ebony and Vestigial- 150 A) Write down all crosses set up to obtain this results (use the lab manual). Deal with one cross at a time: P 1, F1, F2. Set up a Chi square table with the results above. B) Calculate Chi-square and p-value for the results. State whether you will accept or reject your hypothesis. 4. Discussion -discuss your results in context of what is known about autosomal inheritance patterns in Drosophila and you understanding of your hypothesis
Jenny W.
4. How does crossing-over affect the observed outcomes? Explain why the observed flies do not match your prediction. 5. The percentage of crossing over events is used to develop a map of chromosomes. View the chromosome map on the last page. How far apart are the alleles for black body and vestigial wings? (Do the math!) View the proportion of flies from your data that indicate crossover occurred (VG and BL flies) and multiply it by 100. Based on your data, how far apart are these alleles?
Josee P.
8. Describe the changes in genotypic frequencies. (2 points) 9. Compare your final allelic and genotypic frequencies with those of the starting population. (2 points) 10. If you can, formulate a general summary statement or conclusion. (2 points) 11. Would you expect your results to be the same if you had chosen different starting allelic frequencies? Explain. (2 points) 12. Critique your experimental design. (2 points)
Sri K.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD