Muscle Tissue Review
1. What is a sarcomere?
2. What is the function of t-tubules?
3. What is stored in the sarcoplasmic reticulum?
4. What is the cell membrane of a muscle fiber called?
5. What are the components of a triad?
6. Draw a cross-section of a skeletal muscle with the epimysium, perimysium, and endomysium, as well as fascicles, muscle fibers, and myofibrils.
7. Thick filaments are found in bands and made of proteins called.
8. Thin filaments are found in bands and made of three proteins called.
9. Which of the three proteins in thin filaments covers the active sites on f-actin strands?
10. What is the function of troponin?
11. What can bind to troponin?
12. When a muscle fiber is at rest, molecules cover the myosin binding site (actin's active site).
13. How can actin's active site become exposed so that myosin can bind to actin?
14. What is the neurotransmitter that is released from motor neurons that will activate a skeletal muscle?
15. This neurotransmitter will open channels in the muscle fiber that allow:
a. sodium into the cell
b. potassium into the cell
c. acetylcholine into the cell
d. calcium into the cell
15. What happens to a muscle fiber's membrane (sarcolemma) once the motor neuron releases the neurotransmitter listed above?
16. What is the trigger that causes the sarcoplasmic reticulum to release calcium ions into the cell?
17. When calcium binds to troponin/tropomyosin, what happens to actin's active sites (myosin binding sites)?
18. Draw the components of a sarcomere (A band, Z lines, etc.), label the various regions, and be able to describe whether each one of these regions changes (increases or decreases in size) or stays the same when a muscle is contracting.
From the information above and a review of your notes, you should be able to
- Understand the anatomy of a skeletal muscle, its components, and individual muscle fibers.
- Understand how you depolarize muscle fibers
- Understand the process of muscle contraction, from neurons activating muscles, to muscle contraction and relaxation
- Know where the various chemical and voltage gated channels are located, what ions they allow to diffuse through, and what the function of those ions are.
- Know the role of ACHE (acetylcholinesterase)
- Know the energy sources for ATP production in muscles and what ATP is used for.