Question

(a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical formula: ? = (?max * Cs) / (ks + Cs) where ? is the specific growth rate (mol m?³ s?¹), ?max is the maximum specific growth rate (mol m?³ s?¹), ks is a saturation constant (mol m?³) and Cs is the concentration of the limiting substrate (mol m?³). (i) Describe the information that can be gained from this formula and its limitations. (ii) Suggest a bioprocess scheme that this formula can describe. (b) A batch bioreactor at 37°C is used to perform a bioprocess. Assume you are using as nutrient source a complex mixture of sugars that requires an enzyme to be broken to glucose and other monomers. (i) Sketch and discuss the evolution of the biomass concentration as a function of time. (ii) Sketch and discuss the evolution of the product concentration (antibiotic) as a function of time. (iii) Discuss how the productivity will be altered if the reactor temperature was increased to (i) 45°C and (ii) 67°C

          (a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical formula:
? = (?max * Cs) / (ks + Cs)

where ? is the specific growth rate (mol m?³ s?¹), ?max is the maximum specific growth rate (mol m?³ s?¹), ks is a saturation constant (mol m?³) and Cs is the concentration of the limiting substrate (mol m?³).

(i) Describe the information that can be gained from this formula and its limitations.

(ii) Suggest a bioprocess scheme that this formula can describe.

(b) A batch bioreactor at 37°C is used to perform a bioprocess. Assume you are using as nutrient source a complex mixture of sugars that requires an enzyme to be broken to glucose and other monomers.

(i) Sketch and discuss the evolution of the biomass concentration as a function of time.

(ii) Sketch and discuss the evolution of the product concentration (antibiotic) as a function of time.

(iii) Discuss how the productivity will be altered if the reactor temperature was increased to (i) 45°C and (ii) 67°C

(a) The Monod equation describing microbial growth in a CSTR is given by the following mathematical formula:
? = (?max * Cs) / (ks + Cs)

where ? is the specific growth rate (mol m?³ s?¹), ?max is the maximum specific growth rate (mol m?³ s?¹), ks is a saturation constant (mol m?³) and Cs is the concentration of the limiting substrate (mol m?³).

(i) Describe the information that can be gained from this formula and its limitations.

(ii) Suggest a bioprocess scheme that this formula can describe.

(b) A batch bioreactor at 37°C is used to perform a bioprocess. Assume you are using as nutrient source a complex mixture of sugars that requires an enzyme to be broken to glucose and other monomers.

(i) Sketch and discuss the evolution of the biomass concentration as a function of time.

(ii) Sketch and discuss the evolution of the product concentration (antibiotic) as a function of time.

(iii) Discuss how the productivity will be altered if the reactor temperature was increased to (i) 45°C and (ii) 67°C

Added by Mario J.

Question

Please give Ace some feedback