Progressive dysfunction of two or more organ systems, often resulting from an uncontrolled inflammatory response to severe illness or injury, is referred to as: O multiple organ dysfunction syndrome O distributive shock O disseminated intravascular coagulation O systemic inflammatory response syndrome
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Systemic inflammatory response syndrome is caused by: A. Bacterial cells releasing toxic oxygen radicals B. Bacterial cells releasing proteases that degrade the host's tissues C. Immune cells damaging the host's tissues D. Immune cells phagocytosing bacterial cells
Sri K.
_________refers to a loss of blood pressure resulting from a system-wide infection.
If a gram-negative bacterial infection reaches the bloodstream, large quantities of LPS can be released into the blood, resulting in a syndrome called septic shock. Death due to septic shock is a real danger. The overwhelming immune and inflammatory responses that occur with septic shock can cause a perilous drop in blood pressure; intravascular blood clotting; development of thrombi and emboli that block blood vessels, leading to tissue death; failure of multiple organs; and death of the patient. Identify and characterize two to three therapies that might be useful in stopping the dangerous events and outcomes of septic shock once it has begun, given what you have learned about inflammation and innate immunity in this chapter.
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