Put the life cycle of an erythrocyte in order, beginning with their formation in red bone marrow. Erythrocytes form in red bone marrow. Hemoglobin is converted to biliverdin. Erythrocytes circulate for 120 days in the bloodstream. Erythrocytes are phagocytized in the liver and spleen.
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Red blood cells, which carry oxygen to body tissues, live for only about 120 days. Replacement cells are produced by cell division in bone marrow. How many cell divisions must occur each second in your bone marrow just to replace red blood cells? Here is some information to use in calculating your answer: There are about 5 million red blood cells per cubic millimeter $\left(\mathrm{mm}^{3}\right)$ of blood. An average adult has about $5 \mathrm{L}(5,000$ $\mathrm{cm}^{3}$ ) of blood. (Hint: What is the total number of red blood cells in the body? What fraction of them must be replaced each day if all are replaced in 120 days?
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