00:01
Hi, in this question we need to deeply discuss the importance of glutathione in the cell production as well as we need to outline about how glutathione is involved in the detoxification, detoxification of chlorobenzene and we need to tell about the merca, mercapturic acid, mercapturic acids that are usually excreted in urine following the glutathione conjugation of the toxic species.
00:54
So the first step in the metabolism of ethanol that is the acetyl, acetyl aldehyde by the alcohol dehydrogenase adh.
01:19
So acetyl aldehyde is the oxidized, it is oxidized to the acetate by the aldehyde dehydrogenase enzyme.
01:37
So the acetate is then now converted into the acetyl coenzyme a which can be entered into the citric acid cycle and the enzyme adh and aldh are located in the cytosol and mitochondria.
02:02
So the oxidation of the ethanol to acetyl aldehyde that is the reduction series or reduction reaction so which is catalyzed by the adh.
02:26
So the reaction requires the cofactor nad ion which is reduces to the nadh and the oxidation of the acetate to the acetyl aldehyde coenzyme a that is catalyzed by the acetyl coenzyme a synthetase enzyme.
02:47
So the reaction requires the cofactor coenzyme a which is then converted to the acetyl coenzyme a.
02:58
So the metabolism of ethanol it is regulated by the rate of the entry of the acetyl coenzyme in the citric reaction...
