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Question 1: Which of the following is true of the BRCA1 gene? A. Its product normally functions in DNA repair B. Germ-line mutations in this gene are associated with an increased risk for breast and ovarian cancers C. Somatic mutations in this gene are associated with an increased risk for ovarian cancer D. A, B, and C E. None of the above Question 2: Which of the following types of mutations are advantageous to cancer cell growth? A. Those resulting in defective mismatch repair B. Inherited defects in double-strand DNA repair C. A defect in nucleotide-excision repair D. A, B, and C E. None of the above Question 3: The DNA polymerase pol-δ A. Is involved in DNA synthesis B. Is involved in proofreading newly synthesized DNA C. Exhibits exonuclease activity D. A, B, and C E. None of the above

          Question 1: Which of the following is true of the BRCA1 gene?
A. Its product normally functions in DNA repair
B. Germ-line mutations in this gene are associated with an increased risk for breast and ovarian cancers
C. Somatic mutations in this gene are associated with an increased risk for ovarian cancer
D. A, B, and C
E. None of the above

Question 2: Which of the following types of mutations are advantageous to cancer cell growth?
A. Those resulting in defective mismatch repair
B. Inherited defects in double-strand DNA repair
C. A defect in nucleotide-excision repair
D. A, B, and C
E. None of the above

Question 3: The DNA polymerase pol-δ
A. Is involved in DNA synthesis
B. Is involved in proofreading newly synthesized DNA
C. Exhibits exonuclease activity
D. A, B, and C
E. None of the above

Added by Emily A.

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