00:01
First of all, let's discuss the life cycle of plosmodium.
00:05
Plosmodeum is the protozoa or parasite that will actually cause the disease malaria, especially in a lot of underdeveloped area in developing countries.
00:16
So it all start from a mosquito, which is a vector.
00:22
The mosquito, anophilous mosquitoes, usually bites a human that are infected with the malaria.
00:28
So it carries the spores of the plasmidium.
00:35
So when the mosquito bites another human, the spores or sporozoids in the saliva of the mosquito are injected into the bloodstream of them.
00:49
So now it starts the first stage of the life cycle we call exo aerosocytic state.
00:56
Axel means outside.
00:58
Aerithrocytic means blood cells.
01:00
So the first stage of the post -lasmodium infection happens in the liver cell of the bitten human.
01:08
So what happened was the sporozoides infect the liver of the human first.
01:15
For some species, it might go into this stage with the patient.
01:22
The patient has not shown in the clinical symptoms.
01:25
It is in a, i guess, incubation period that sometimes when the, system is lower, it's going to eventually break out.
01:34
But most of the species don't have the stage.
01:38
So once the sporozoitis infect liver cell, they would affect the heptocytes liver cell.
01:44
And inside of a liver cell, they produce this haptic sphazone, which is like a cell that multiply the sporozoitis inside with a grain circles inside.
01:57
So when these habitat disease matured, they actually ruptured.
02:04
As you can see, after the rupturing happens, the scores actually are released into the blustering of patients.
02:15
Now, this moves into a second stage of the life cycle of plasmodium.
02:21
We call it every throat cycle, which means now the second stage of the plasmodium infection occurs in the reblos cell.
02:29
Now, these green spores now have a different name of the incubation in the liver.
02:37
They are a little different.
02:39
So these scores are called maryzoites.
02:42
Marizotees are able to finally infect the red blood cell.
02:46
As you can see, they capture the red blood cell over there, and then start to incubate and then develop or differentiate inside of the red blood cells.
02:56
So you can see these maryzoites differentiate into the first cell.
03:00
Stage we call the early prophozoites, the rain form.
03:06
And then you can see they start to grow and then multiply.
03:09
And then in this stage, we call it the blood stage schizont, because these red blood cell are infected and carry and multiply these spores.
03:21
Eventually, the red blood cell, again, they were ruptured and released those matured myrolytes into the bloods.
03:29
And then infect more a ribloid cell.
03:35
So it's a vicious cycle.
03:37
Now, both the axel erythrocyte thick stage and erythrocyte thick stage, they're asexual life cycle.
03:49
And you can see some of the early trophosezoatees, they actually differentiate into something else.
03:57
We call it gametocytes.
03:59
So these are actually the same.
04:01
Sexual life cycle part of the plasmodium.
04:07
And over there, these are gametes, all right? and then they're in a bloodstream.
04:12
And during this stage, another mosquito that will actually bite the patient...