Question 13
A team of researchers conducted a valid prospective cohort study analyzing several exposures for their association with heart disease. They gathered data on smoking, blood pressure, diabetes, and exercise patterns among other factors. They found that the relative risk for developing heart disease for smokers was compared to non-smokers. The relative risk for developing heart disease for people with high blood pressure was compared to those without high blood pressure. The relative risk for developing heart disease for people with diabetes was 2 compared to people without diabetes. The relative risk for developing heart disease among people who exercised regularly was 0.7 compared to people who did not exercise regularly. Based on these findings, which exposure had the strongest association with heart disease? Smoking, High Blood Pressure, Diabetes, or Regular exercise?
Question 14
A study of the possible association between alcohol drinking (exposure) and developing cancer (outcome) found that the association is distorted by the presence of a third variable in this case. In this example, the third variable is an example of a confounder.
Question 15
A researcher wants to study the effect of a new medicine in preventing hip fractures. They ask you to advise them on ways to manage confounding in the study. You correctly inform them that confounding can be decreased by randomizing subjects into study groups.