Question 18 of 60 Chimeric antigen receptor T-cell therapy was first indicated for patients with what diagnosis?
Added by John Q.
Close
Step 1
Step 1: Chimeric antigen receptor T-cell (CAR T-cell) therapy is a type of immunotherapy that uses a patient's own immune cells to fight cancer. Show more…
Show all steps
Your feedback will help us improve your experience
Sanchit Jain and 69 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Chimeric antigen receptor T-cell therapy was first indicated for patients with what diagnosis? A. Non-Hodgkin's lymphoma B. Chronic lymphocytic leukemia C. T-cell lymphoblastic lymphoma D. B-cell acute lymphoblastic leukemia
Sanchit J.
History and Physical Examination This family had a son who had died at the age of 2 weeks because of an overwhelming bacterial infection. When their newborn daughter began developing recurrent infections, she was immediately taken to a pediatrician. Laboratory Data Hemoglobin and hematocrit—within normal range. Total WBC count—62.0x10^9/L Absolute leukocyte counts—above normal for each leukocyte type Leukocyte differential—neutrophils 76%, lymphocytes 22%, eosinophils 2% Flow cell cytometry T lymphocytes—normal proportion of CD4+ and CD8+ cells B Lymphocytes (CD19+)—elevated Natural Killer (NK) cells—elevated CD18+ lymphocytes—5% Treatment The infant was given busulfan, cyclophosphamide, and antithymocyte serum for 10 days. She received mature T lymphocyte-depleted bone marrow transplanted from her mother. This was followed by a short period of suppressive therapy. She recovered from the procedures and did well clinically. Questions 1. What laboratory test is of the greatest diagnostic value in diagnosing this patient? 2. What value in the reported flow cytometry results is diagnostic? 3. Can leukocyte adhesion be misdiagnosed?
Adi S.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD