46,XX Question 3 of 5 of Mid-semester project Value = 15...

46,XX Question 3 of 5 of Mid-semester project Value = 15 points Your answer should be between ½ to 1 page typed in accordance with the font size, type, and writing guidance on the syllabus. X-inactivation is described as random among different cells in any given individual female. Why is it that some disorders, described as X- linked recessive, demonstrate no or minimal phenotypic affects in the carrier female if, according to probability of random X- inactivation, about half of her X chromosomes that harbor the mutation would express the mutation and the other half of her X- chromosomes that harbor the mutation would not? Hint: Use the figure to the right to begin to formulate an answer to this question.

Transcript

00:01 Hello everyone in this question we will be discussing about meiosis.

00:06 Meiosis is a reductional division and with the procedure of meiosis, gametes are produced, that is somatic cells are deployed and from it through meiosis 1, 2 haploid cells are produced.

00:26 And after meiosis we have four haploid gametic cells.

00:32 And the gamete cells are haploid in nature because then only the egg and the sperm will fuse together and will produce a diploid zygod.

00:46 That is the normal zygote here.

00:48 So that is why the meiosis produce the gametes.

00:52 So the meiosis is divided into subloid.

00:56 Certain steps.

00:57 The first phase is the interphase.

01:00 This is known as this is basically known as the preparatory phase which is divided into g1 s and g2 phase.

01:11 In the g1 there is protein synthesis and also organal replication takes place here.

01:19 In the s phase the dna replication takes place as well as the centrosome replicates.

01:30 So the number of chromosomes remains the same but the dna content double and the number of chromosome remains the same because the two chromatids are attached to one centromere and in the g2 phase the rest of the organelles that is mitochondria and chloroplast replicates as well as the cell becomes ready to enter into the m phase.

01:56 Now in the m phase, the first stage is the pro phase, which is further divided into leptotene, zygotein, cygotein, cygotein, typtin, and dikinesis.

02:16 In the leptotene stage, the chromosome condensation takes place and the nuclear membrane, the organelles disappear.

02:29 In the zygotin stage there is formation of synaptanimal complex between two of the homologous chromosome.

02:39 Suppose this is one chromosome and this is the homologous chromosome between which the crossing over has to take place.

02:48 So in between them there will be formation of a synaptanimal complex and in the pecytitin stage the crossing over takes place.

02:58 In the diplotene stage, the crossing over has been done but the chromosome are still attached to each other at the place of chies marta, which is the site of crossing over.

03:13 And in the diachynesis, the chromosome separate from each other and the chromosome has been completed...

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