Question 3. Which of the following statements is false? (1 point) (a) Tumor progression results from the stepwise accumulation of DNA mutations in cancer cells. (b) The normal function of oncogenes is to activate cell division and the mutations that cause cancer are "gain of function." (c) For oncogenes, overexpression of the "normal" protein has the same consequence as a gain of function mutation in the protein. (d) The normal function of tumor suppressor genes is to inhibit cell division and the mutations that cause cancer are "loss of function." (e) Mutations do not occur in normal healthy cells unless they are exposed to certain environmental factors such as radiation or harmful chemicals.
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Which of the following statements about cancer is false? (a) Oncogenes arise from mutations in proto-oncogenes. (b) Tumor suppressor genes normally interact with growth-inhibiting factors to block cell division (c) More than 100 oncogenes and 15 tumor suppressor genes have been identified (d) Oncogenes were first discovered in mouse models for cancer (e) The development of cancer is usually a multistep process involving both oncogenes and mutated tumor suppressor genes
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