Question 31 What type of antiviral agent would work against retroviruses such as HIV, but not against non-retroviral viruses? uncoating inhibitors protease inhibitors receptor blocking agents reverse transcriptase inhibitors
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Which of the following chemical therapies will likely preserve the CD4 cell genome/nucleus ? Protease inhibitors Reverse transcriptase inhibitors Lysis inhibitors Glycosylation inhibitors
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Mark all of the answers that are TRUE regarding ARVs. Select one or more: a. The nucleoside analogs (NRTIs) act by promoting DNA chain elongation b. NNRTIs, such as Nevirapine, act by binding directly to reverse transcriptase, inhibiting its efficiency. c. T20 (Fuzeon) acts by blocking viral envelope and host cell membrane fusion. Mark all of the answers that are TRUE. Select one or more: a. A mutation that results in a variant HIV strain resistant to a drug can often affect the entire drug class. b. Multi-class ARVs offer inexpensive options for controlling viral loads. c. NRTIs block reverse transcription by prematurely terminating DNA synthesis. d. Entry inhibitors, like Maraviroc, and integrase inhibitors, like Raltegravir, are the first members of the new classes of HIV antiretrovirals. e. The nucleotide RT inhibitor, Tenofovir, has demonstrated more side effects compared to most nucleoside RT inhibitors.
Which of the following statements is false concerning antiviral drugs? a. Macrolide drugs block attachment sites on the host cell wall and prevent viruses from entering. b. Drugs that neutralize the acidity of phagolysosomes prevent viral uncoating. c. Nucleotide analogs can be used to stop microbial replication. d. Drugs containing protease inhibitors retard viral growth by blocking the production of essential viral proteins.
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