00:01
Mediators regulate the gene expression, regulate the gene expression in eukaryotes, the gene expression in eukaryotes, eukaryotes by first thing is that mediator is a large protein complex, mediator is a large protein complex, large protein complex that interact with the, that interact with the transcription factors, that interact with the transcription factors and rna polymerase too.
01:14
And rna polymerase too, which is the, which initiates the transcription, also catalyzes the reaction or adds the base pairs.
01:32
So, mediator is a large protein complex that interact with the transcription factors like initiation factor, release factor and rna polymerase too.
01:45
Then it helps, mediator helps to recruit transcription, helps to recruit transcription factors, transcription factors which play very important role in transcription to dna and also helps to position rna also helps to position rna.
02:27
Position rna polymerase too, position rna polymerase too at the correct location of the dna, at the correct location of dna or we can say at the promoter region of dna, location of the dna...