Question

Question: Mutations in the tumor suppressor gene BRCA1 can lead to breast and ovarian cancer. A point mutation in the promoter of BRCA1 leads to less efficient translation of the BRCA1 protein. As a result, cells go into uncontrolled proliferation and form tumors. This mutation is most likely (Highlight Answer): A) Dominant Negative mutation B) Nonsense mutation C) Gain-of-function mutation D) Loss-of-function mutation Explain your answer:

Name: question mutations in the tumor suppressor gene brca1 can lead to breast and ovarian cancer a point mutation in the promoter of brca1 leads to less efficient translation of the brca1 protein 09872
Uploaded: 2022-04-22T11:50:29-08:00
Duration: 1 min 42 s
Channel: Marlyn Joyce
Description: question mutations in the tumor suppressor gene brca1 can lead to breast and ovarian cancer a point mutation in the promoter of brca1 leads to less efficient translation of the brca1 protein 09872

          Question:
Mutations in the tumor suppressor gene BRCA1 can lead
to breast and ovarian cancer. A point mutation in the promoter of
BRCA1 leads to less efficient translation of the
BRCA1 protein. As a result, cells go into uncontrolled
proliferation and form tumors.
This mutation is most likely (Highlight
Answer):
A) Dominant Negative
mutation           
B) Nonsense mutation
C) Gain-of-function mutation    
           
D) Loss-of-function mutation
Explain your answer:

Added by Jennifer S.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Marlyn Joyce

04/22/2022

Step 1

Step 1: Tumor suppressor genes inhibit cell proliferation and their loss can lead to cancer. Show more…

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Question: Mutations in the tumor suppressor gene BRCA1 can lead to breast and ovarian cancer. A point mutation in the promoter of BRCA1 leads to less efficient translation of the BRCA1 protein. As a result, cells go into uncontrolled proliferation and form tumors. This mutation is most likely (Highlight Answer): A) Dominant Negative mutation B) Nonsense mutation C) Gain-of-function mutation D) Loss-of-function mutation Explain your answer: