00:01
The first question is asking for which signaling pathway the cytokines are used as ligand.
00:12
So the answer is option a, that is the jackstart pathway.
00:23
On the other hand, the pi3 kinase pathway uses insulin as ligand, whereas the rasma pathway uses growth factors as ligand.
00:38
The second question is asking for the mechanism of action of lipid soluble hormones.
00:45
Say this is the lipid soluble hormone which is represented by.
00:48
The green circle.
00:52
One of the property of these lipid soluble hormones is they can easily cross the phospholipid bilayer of the plasma membrane.
00:58
This is the lipid bilayer of the plasma membrane.
01:03
And after crossing the phospholipid bilayer, they enters into the cytosol, where they can either bind to the cytosolic receptor.
01:10
This is the cytosolic receptor for that particular lipid soluble hormone.
01:15
Or they can cross the plasma membrane of the nucleus and binds to the nuclear receptor.
01:21
This is the lipid soluble hormone that is binding to the nuclear receptor...