Accumulation of acetyl-CoA in the mitochondria of the liver may lead to the formation of ketone bodies. Select one: True False Which of the following is (are) ketone body(ies): Select one: a. acetoacetate b. acetone c. ?-hydroxy butyrate d. all of the above
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Step 1: Accumulation of acetyl-CoA in the mitochondria of the liver can lead to the formation of ketone bodies. Show more…
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31. Which one of the following is not a reason why ketone bodies are made? A) To prevent buildup of acetyl-CoA in the liver B) The citric acid cycle slows down during starvation conditions as its intermediates get depleted for other pathways C) To produce acetyl-CoA in the liver D) To provide acetyl-CoA in tissues outside the liver E) To provide CoASH to the liver 32. The following fatty acid, in which the indicated carbon atom is radiolabeled as 14C, is fed to an experimental mammal: 14CH3(CH2)15COOH After allowing sufficient time for fatty acid oxidation, the 14C label would be found temporarily in which one of the following compounds? A) beta-hydroxy butyryl-CoA B) acetyl-CoA C) propionyl-CoA D) malonyl-CoA E) bicarbonate EXTRA CREDIT (2 pts) 33. The 20:2(Δ10,15) fatty acyl-CoA shown below is undergoing beta-oxidation in the liver. How many total ATP molecules would be generated by the complete beta-oxidation of one molecule of this fatty acyl-CoA (including metabolic processes subsequent to beta-oxidation)? Write your answer on the blank below. (1 FADH2 : 1.5 ATP ; 1 NADH : 2.5 ATP) A) 136 ATP B) 134.5 ATP C) 133 ATP D) 130 ATP E) 132 ATP
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In a fasted state: HMG-CoA synthase activity will increase, leading to ketone body production. Acetyl-CoA levels in the liver will accumulate due to increased use of OAA for GNG, leading to ketone body production. Ketone body concentration in the blood will increase significantly. Fatty acid synthase activity will be low. All of the above.
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Which of the following statements about the metabolism of ethanol (which is present in alcoholic beverages) is incorrect? a) Individuals who produce non-functioning aldehyde dehydrogenase exhibit "fastflushing." b) The process requires two enzymes: alcohol dehydrogenase and isopropyl dehydrogenase. c) Individuals who are "fast-flushers" are less likely to become alcoholics. d) Aspirin interferes with the action of alcohol dehydrogenase. e) All of the above are correct.
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