00:01
This question asks us to rationalize the following statement.
00:06
The statement is toddlers who are administered frequent rounds of antibiotic treatment will suffer an inefficient immune system.
00:13
So we have four choices to give the rationale for that statement.
00:18
Choice a, antibiotics suppress inflammation as well as killing pathogens.
00:23
And since inflammation is a mechanism of defense, the toddler will lack that important process.
00:28
B, antibiotics will kill the microbiome as well as any pathogens, which affects immune function, since the microbiota release chemicals that affect the maturation and homeostasis of innate leukocytes or white blood cells.
00:50
C, antibiotics kill innate white blood cells as well as any pathogens.
00:56
D, antibiotics will kill the microbiome instead of the pathogens, since they are more abundant, thereby preventing the process of colonization resistance.
01:13
Well, let's start with eliminating incorrect choices...