Mechanisms of Drug Action on Bacterial Cells Drag and drop...

Mechanisms of Drug Action on Bacterial Cells Drag and drop each term to its respective location on the diagram. Site of action: 50S subunit Azithromycin Synercid Pleuromutilins Site of action: 30S subunit Aminoglycosides Streptomycin Tetracyclines Glycylcyclines Both 30S and 50S: Blocks initiation of protein synthesis Linezolid Substrate Enzyme Product DNA Block synthesis and repair Penicillins Cephalosporins Carbapenems Vancomycin Bacitracin Isoniazid Cause loss of selective permeability Polymyxins (colistins) Daptomycin Inhibit replication and transcription Inhibit gyrase (unwinding enzyme) Quinolones

Transcript

00:01 Hello students, in this question we have been given certain options and based on those options we have to identify the answers.

00:11 Cipro is the brand name for the fluoroquinoline antibiotic, fluoropinolone the enzyme responsible for unwinding dna during replication.

00:22 What is this drug's mechanism of action? so what is happening is that dna replications.

00:30 Is affected.

00:32 So it is acting as an inhibition, inhibition of replication.

00:46 So this is the answer.

00:49 Isonized is the one of the few drugs that can be used against mycobacterium infections because it can target the compound mycolic acid.

00:58 What is the mode of action? it is the inhibition of cell wall synthesis.

01:06 So 34 answer is.

01:08 A.

01:12 Erythromycin binds to the large subunit of the dash preventing mrna, translation and inhibiting protein synthesis, subunit of ribosome.

01:23 So the answer is ribosome option ac.

01:28 Penicillin is considered narrow spectrum because it targets the peptidoglycan in gram positive bacteria.

01:36 The action of this drug is described as the dash.

01:41 It is the disruption of cytoplasmic membrane.

01:50 Option b.

01:53 The antibiotic tetracycline blocks the docking site for trna.

01:58 The mechanism of action of tetracycline is described as the inhibitor of protein synthesis.

02:06 So option c.

02:10 So now let's look at the true or false statements.

02:14 Antimicrobial that are, whichever sentences are true, you will write a and for false we'll write b.

02:22 Antimicrobials that are made by organism in nature are called semi -synthetic.

02:27 No.

02:28 They are natural antimicrobials...

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