Select all of the TRUE statements regarding antibodies. (Mark all that apply) a. All classes of antibodies can lead to activation of the classical complement pathway. b. Antibodies are composed of two heavy chains and two light chains that are held together by disulfide bonds. c. The variable region of a heavy chain and light chain binds to the epitope. d. The Fc region of an antibody may bind to a host cell or other antibodies. e. The constant region of a heavy chain is the same for all antibodies. f. Antibodies may be secreted by plasma cells or function as B-cell receptor (BCR).
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Which of the following statements about B cells/antibody production is false? a) $\mathrm{B}$ cells of a given specificity initially have the potential to make more than one class of antibody. b) In response to antigen, all $\mathrm{B}$ cells located close to the antigen begin dividing. c) Each $\mathrm{B}$ cell is programmed to make a single specificity of antibody. d) The B-cell receptor allows B cells to detect antigen. e) The cell type that makes and secretes antibody is called a plasma cell.
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