Question

1- For a typical vertebrate cell with a transmembrane potential of -0.070 V (inside negative), what is the free energy change for transporting 1 mol of Na+ out of the cell and into the blood at 37 °C? Assume the concentration of Na+ inside the cell is 12 mM and that in blood plasma is 145 mM. answer: 17.13 kj/mol 2- A human erythrocyte has about 2 X 10^5 Aquaporin (AQP) monomers. If water molecules flow through the plasma membrane at a rate of 5 X 108 per AQP tetramer per second, and the volume of an erythrocyte is 5 X 10^-11 mL, how rapidly could an erythrocyte halve its volume as it encountered the high osmolarity (1M) in the interstitial fluid of a renal medulla? Assume that the erythrocyte consists entirely of water. answer: 23. 3*10^-2 s

          1- For a typical vertebrate cell with a transmembrane
potential of -0.070 V (inside negative), what is the free energy
change for transporting 1 mol of Na+ out of the cell and into the
blood at 37 °C? Assume the concentration of Na+ inside the cell is
12 mM and that in blood plasma is 145 mM. 
answer: 17.13 kj/mol
2- A human erythrocyte has about 2 X 10^5 Aquaporin
(AQP) monomers. If water molecules flow through the plasma membrane
at a rate of 5 X 108 per AQP tetramer per second, and the volume of
an erythrocyte is 5 X 10^-11 mL, how rapidly could an erythrocyte
halve its volume as it encountered the high osmolarity (1M) in the
interstitial fluid of a renal medulla? Assume that the erythrocyte
consists entirely of water. 
answer: 23. 3*10^-2 s

Added by Blanca G.

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